Name: | Octreotide |
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Item Code: | HG025 |
CAS Number: | 79517-01-4 |
Other name: | Octreotide |
Molecular formula: | C49H66N10O10S2 |
Molecular mass: | 1019.26 |
Sequence: | H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol (Disulfide bond) |
Purity: | >98% |
Main usage: | Acromegaly, Carcinoid syndrome, VIPomas |
Product Description
Octreotide Acetate is a longer acting synthetic octapeptide analog of naturally occurring somatostatin. Octreotide Acetate inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormone. Octreotide reduces gastrointestinal motility and inhibits contraction of the gall bladder.
【Test】 | 【Specifications】 |
Appearance | White to off-white amorphous powder |
Solubility | Soluble in water and 1% acetic acid at a concentration of ≥ 1 mg/mL to give a clear, colorless solution |
Identification By HPLC | Retention time is same with the reference substance |
Molecular Ion Mass | 1019.3±1 |
Specific optical rotation | -17 °to -21° |
Amino Acid Composition | ±10% |
Purity (HPLC) : | NLT 98.0 % |
Related Substances(HPLC) | Total impurities <2.0% Any individual impurity: <0.5% [des-Thr-ol8]-Octreotide≤2.0% |
Acetic acid (HPLC) | 5.0 to 12.0% |
pH (10 mg/mL in water) | 5 to 7 |
Water Content(Karl Fischer) : | ≦10 % |
Peptide Content : | NLT 80% |
Residual Solvents(Acetonitrile) | ≦0.05% |
Assay(Mass balance) | 95.0~105.0% |
Bacterial Endotoxins : | ≦5EU/mg |