| Name: | Goserelin |
|---|---|
| Item Code: | HG019 |
| CAS Number: | 145781-92-6 |
| Other name: | Goserelin |
| Molecular formula: | C59H84N18O14 |
| Molecular mass: | 1269.43 |
| Sequence: | Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2 |
| Purity: | ＞98% |
| Main usage: | Advanced hormone-dependent prostate cancer, Advanced hormone-dependent breast cancer, Endometriosis, Uterine myoma, Use in reproductive medicine |
Goserelin Acetate is a potent GnRH (LHRH) agonist. After a transient increase, continuous administration of goserelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
【Test】 | 【Specifications】 |
Appearance | White to off-white powder |
Solubility | Soluble in water at a concentration of 30% (w/w) to give a clear, colorless solution. Time to gelling is > 15 minutes. |
Molecular Ion Mass | 1269.42±1 |
Amino Acid Composition | ±20% |
Purity (HPLC) : | ≥ 98% |
Related Substances(HPLC) | Total impurities <2.0% Single impurities <1.0% |
Acetic acid (HPLC) | 4.5%~15 % |
Water Content(Karl Fischer) : | ≦10.0 % |
Peptide Content : | NLT 80% |
Assay(By Anhydrous, Acetic Acid-free) | 95.0～105.0％ |
Bacterial Endotoxins : | ≦16 EU/mg |
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