Name: | Glucagon |
---|---|
Item Code: | HG018 |
CAS Number: | 16941-32-5 |
Other name: | Glucagon |
Molecular formula: | C153H225N43O49S |
Molecular mass: | 3482.80 |
Sequence: | H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH |
Purity: | >98% |
Main usage: | Hypoglycemia (diabetes mellitus) |
Product Description
Glucagon is produced in the α-cells of the islets of Langerhans. The hormone opposes the action of insulin. Glucagon promotes the synthesis and mobilization of glucose from glycogen in the liver. The generation of glucose from lipids is regulated by glucagon as well.
Additionally, glucacon induces inotropic and chronotropic effects by raising the concentration of cAMP.
【Test】 | 【Specifications】 |
Appearance | White powder |
Solubility | Very soluble in water (>1mg/ml) |
Identification By HPLC | Retention time is same with the reference substance |
Molecular Ion Mass | 4186.6±1 |
Purity (HPLC) : | NLT 98.0 % |
Related Substances(HPLC) | Total impurities <2.0% Single impurity: <1.0% |
Chloride | ≦10 % |
Water Content(Karl Fischer) : | ≦8 % |
Peptide Content : | NLT 80% |
Residual Solvents(Acetonitrile) | ≦0.041% |
Assay(By Anhydrous, HCL-free) | 95.0~105.0% |
Bacterial Endotoxins : | ≦10IU/mg |