| Name: | Protirelin |
|---|---|
| Item Code: | HG027 |
| CAS Number: | 24305-27-9 |
| Other name: | TRH, Thyrotropin-releasing hormone |
| Molecular formula: | C16H22N6O4 |
| Molecular mass: | 362.39 |
| Sequence: | Pyr-His-Pro-NH2 |
| Purity: | ＞98% |
| Main usage: | Diagnosis of pituitary and thyroid function |
Protirelin, also known as thyrotropin-releasing hormone (TRH), causes the secretion of thyroid-stimulating hormone (TSH) from the anterior pituitary gland. TSH acts on the thyroid gland to release the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Additionally, protirelin shows prolactin-releasing activity.
【Test】 | 【Specifications】 |
Appearance | White powder |
Solubility | Very soluble in water (>1mg/ml) |
Identification By HPLC | Retention time is same with the reference substance |
Molecular Ion Mass | 362.39±1 |
Amino Acid Composition | ±10% |
Purity (HPLC) : | NLT 98.0 % |
Related Substances(HPLC) | Total impurities <2.0% Single impurity: <1.0% |
Acetic acid (HPLC) | <12.0 % |
Water Content(Karl Fischer) : | ≦8.0 % |
Peptide Content : | NLT 80% |
Residual Solvents(Acetonitrile) | ≦0.041% |
Assay | 95.0～105.0％ |
Bacterial Endotoxins : | ≦5EU/mg |
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