PEG-MGF is the Pegylated form of MGF (Mechano Growth Factor). MGF is a splice variant of IGF-1, which has been shown in vitro as well as in vivo to induce growth and hypertrophy in mechanically stimulated or damaged muscle. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes.

PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down. Insulin-like growth factor genes appear to have evolved from a single insulin-like gene. This gene can be detected in invertebrates and seems to cause anti-apoptotic effects by maintaining terminally differentiated cells. MGF contains the core protein encoded by the exons 3 and 4, as well as a specific insert encoded by a region of exon 5.

Specification

Appearance

White to off-white amorphous powder

Molecular Ion Mass

2888.16 ±1

Amino Acid Composition

±10%

Purity (HPLC) :

NLT 98.0 %

Related Substances

Total impurities <2.0%

Any individual impurity: <1.0%

Acetic acid (HPLC)

≤15.0%

Water Content

≦8%

What makes MGF special is its’ unique role in muscle growth.  MGF has the ability to cause wasted tissue to grow and improve by activating muscle stem cells and increasing the upregulation of protein synthesis, this unique ability can rapidly improve recovery and speed up muscle growth.  MGF can initiate muscle satellite (stem) cell activation in addition to its IGF-1 receptor domain which, in turn, increases protein synthesis turnover; therefore, if used correctly it can improve muscle mass over time. I summary, it helps,

Increases muscle protein synthesis, which promotes muscle growth

PEG MGF peptide favors the retention of nitrogen, which allows measuring the amount of protein present in the body.

Side effect of PEG MGF 

No specific side effect reported. This peptide can cause redness on the face and itchy skin, which are mainly associated with allergic reactions or as a response to inflammation of the blood vessels of the skin.