Name: | Atosiban |
---|---|
Item Code: | HG003 |
CAS Number: | 90779-69-4 |
Other name: | Atosiban |
Molecular formula: | C43H67N11O12S2 |
Molecular mass: | 994.20 |
Sequence: | 3-Mercaptopropionyl-D-Tyr(Et)-Ile-Thr-Asn-Cys-Pro-Orn-Gly-NH2 (Disulfide bond) |
Purity: | >98% |
Main usage: | Premature labor |
Product Description
Atosiban is an oxytocin and vasopressin antagonist. Atosiban is used as a tocolytic in the management of preterm labor.
【Test】 | 【Specifications】 |
Appearance | White or off-white powder |
Identification By HPLC | Retention time is same with the reference substance |
Amino Acid Analysis | Asp 0.7~1.1 Gly 0.8~1.1 Thr 0.9~1.2 Pro 0.9~1.4 Tyr 0.8~1.2 Ile 0.8~1.2 Cys present |
pH | 4.0~6.0 |
Specific Optical Rotation | -45~-55 º (c=1%,HAc) |
Purity (HPLC) : | NLT 98.5 % |
Related Substances(HPLC) | Impurity A NMT 0.4% Impurity B NMT 0.5% Impurity C NMT 0.5% Any unidentified impurities not more than 0.1% |
Acetic acid (HPLC) | 5.0%~12% |
Water Content(Karl Fischer) : | ≦8.0% |
Residue Solvents: Acetonitrile (ACN) Dichloromethane (DCM) N,N-DimethylFormamide(DMF) Diisopropylether(DIPE) Trifluoroacetic acid(TFA) Ethanol |
≤0.041%(w/w) ≤0.06%(w/w) ≤0.088%(w/w) ≤0.5%(w/w) ≤0.5%(w/w) ≤0.5%(w/w) |
Bacterial endotoxins | NMT 12.2EU/mg |
Assay (By Anhydrous,Acetic Acid-free) | 96.0%~104.0% |