PT 141, sometimes referred to as PT-141 and most recently under the name Bremelanotide is a 7 amino acid peptide that derived from Melanotan II. Melanotan II (MT2) was developed for the purpose of promoting tanning, but more than 90% of all subjects during testing were found to have increases in libido, performance and sexual satisfaction. itused to treat hypoactive sexual desire disorder in premenopausal women. PT 141 does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141. Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women. Bremelanotide was granted FDA approval on 21 June 2019.

Specification

Appearance

White to off-white amorphous powder

Molecular Ion Mass

1025.2 ±1

Amino Acid Composition

±10%

Purity (HPLC) :

NLT 98.0 %

Related Substances

Total impurities <2.0%

Any individual impurity: <1.0%

Water Content

≦8%

The effect of IPT-141 is very direct, it can improve sexual desire (sexual desire), sexual satisfaction and erectile dysfunction.

In modern times, especially with regard to erectile dysfunction, the use of PED5 inhibitors (such as Viagra and Cialis) has dominated. However, it is important to note that PED5 does not affect sexual desire, they only affect erections. A man may still have a strong sexual desire, but cannot get an erection due to blood flow problems. This problem can be solved by using PED5, and this situation often happens.

Another possible problem surrounding erectile dysfunction or decreased libido may be hormone imbalances, such as low testosterone levels. There may be no blood flow problems, but lack of sexual desire due to a lack of major male hormones. In this case, testosterone is usually used to correct the problem. In other cases, there may be low testosterone levels and blood flow problems, and both testosterone and PED5 are used.

Side effect of PT 141

On first use, nausea and vomiting are the two most common side effects, and their incidence is about the same as MT2. Unlike MT2, PT 141 does not seem to have a strong negative impact on appetite in most users.

Other possible side effects of PT 141 include headaches, dizziness, and, in some rare cases, hypertension. Some people will also find irritation at the injection site, such as soreness or bruising, and should rotate or look for a new injection site.